A double-encapsulated extract of Siam water lily stem cells developed by IBHS using polymeric micellar cubic encapsulation technology. This unique and innovative encapsulation system combines the principles of colloidal surface chemistry with pharmaceutical technology, utilizing sub-micron-sized particles. Through polymeric micellar cubic encapsulation, it enhances the solubility and stability of the stem cell extract in the formulation and facilitates the penetration of active ingredients through the skin.